Biography
SUN Hong is a professor and doctoral supervisor. She has presided over several research projects, including general projects of the National Natural Science Foundation of China and international cooperation projects. As the first author and corresponding author, she has published over 100 academic papers in domestic and foreign academic journals, among which more than 50 are SCI papers. She has been granted one national invention patent and three utility model patents. She has won one first prize for scientific and technological progress in Xuzhou City, one first prize, and one-second prize for Huaihai scientific and technological progress. She has compiled three textbooks as the chief editor and has been awarded the Excellent Science and Technology Work Award of Xuzhou Medical University. She also organizes and guides students to participate in international and Chinese regional physiology competitions, as well as the basic medical innovation experimental design competition.
Work experience
2019.06--2021.06, Director, International Cooperation and Exchange Department, XZMU
2011.12--2021.06, Dean, School of International Education, XZMU
2008.07--Present, Professor, Department of Physiology, XZMU
2007.09--2008.06/2001.12--2004.09 Associate professor, Department of Physiology, Xuzhou Medical College (XZMC)
1999.01--2001.12 Assistant Researcher, National Heart and Lung Institute, Imperial College London, UK
1995.09--1999.01 Lecturer, Department of Physiology, XZMC
1988.09--1992.07 Assistant, Department of Physiology, XZMC
Education
2004.09--2007.07 PhD student, Department of Pathophysiology, Nanjing Medical University
1992.09--1995.06 Medical Postgraduate student, Department of Physiology, Peking University Health Science Center
1983.09--1988.06 Medical Undergraduate student, Department of Clinical Medicine, Xuzhou Medical College
Publications
Representative publications:
1. Chen X and Sun H*. The Anxiety and Depression of International Medical Students during COVID-19 Pandemic: A Cross-Sectional Study；Perspectives in Psychiatric Care； 2024, ID 2285597 https://doi.org/10.1155/2024/2285597.
2. Ndzie Noah ML, Mprah R, Wowui PI, Adekunle AO, Adu-Amankwaah J, Tan R, Gong Z, Li T, Fu L, Machuki JO, Zhang S, Sun H*. CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner. Cell Commun Signal. 2024;22(1):166. doi: 10.1186/s12964-024-01535-8.
3. Adu-Amankwaah J, Adekunle AO, Tang Z, Bushi A, Tan R, Fu L, Gong Z, Ma Z, Mprah R, Ndzie Noah ML, Wowui PI, Ong'achwa Machuki J, Pan X, Li T, Sun H*. Estradiol contributes to sex differences in resilience to sepsis-induced metabolic dysregulation and dysfunction in the heart via GPER-1-mediated PPARδ/NLRP3 signaling. Metabolism. 2024 Jul;156:155934. doi: 10.1016/j.metabol.2024.155934. Epub 2024 May 16.
4. Wu J, Feng A, Liu C, Zhou W, Li K, Liu Y, Shi Y, Adu-Amankwaah J, Yu H, Pan X, Sun H*. Genistein alleviates doxorubicin-induced cardiomyocyte autophagy and apoptosis via ERK/STAT3/c-Myc signaling pathway in rat model. Phytother Res. 2024 May 31. doi: 10.1002/ptr.8236.
5. Adu-Amankwaah J, Bushi A, Tan R, Adekunle AO, Adzika GK, Ndzie Noah ML, Nadeem I, Adzraku SY, Koda S, Mprah R, Cui J, Li K, Wowui PI, Sun H*. Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway. Cell Mol Life Sci. 2023 Aug 12;80(9):246. doi: 10.1007/s00018-023-04886-6.
6. Yin ZY, Fu T, He SM, Fu L, Li XZ, Xu L, Du L, Yang TT, Zhu X, Wang C, Qiao WL, Tang ZQ, Zhang XY, Li K, Zhang XY, Gong Z, Zhou XY*, Zhang B*, Sun H*. 16α-OHE1, a novel oestrogen metabolite, attenuates dysfunction of left ventricle contractility via regulation of autophagy after myocardial ischemia and reperfusion. Int J Cardiol. 2023 Oct 1;388:131123. doi: 10.1016/j.ijcard.2023.131123.
7. Adzika GK, Mprah R, Rizvi R, Adekunle AO, Ndzie Noah ML, Wowui PI, Adzraku SY, Adu-Amankwaah J, Wang F, Lin Y, Fu L, Liu X, Xiang J, Sun H*.Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense. Front Immunol. 2023 Feb 15;14:1124649. doi: 10.3389/fimmu.2023.1124649. eCollection 2023.
8. Li W, Gillies RM, Liu C, Wu C, Chen J, Zhang X, Cheng B, Dai J, Fu N, Li L, Liu S, Sun H*. Specialty preferences of studying-abroad medical students from low- and middle-income countries. BMC Med Educ. 2023 Mar 15;23(1):158. doi: 10.1186/s12909-023-04123-5.
9. Ndzie Noah ML, Adzika GK, Mprah R, Adekunle AO, Koda S, Adu-Amankwaah J, Xu Y, Kanwore K, Wowui PI, Sun H*. Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress. Cell Commun Signal. 2023 Feb 23;21(1):41. doi: 10.1186/s12964-023-01052-0.
10. Tao X, Xu Y, Adu-Amankwaah J, Gong Z, Wang Y, Huang F, Sun H*. β2AR against myocarditis-lipid deposition depends on estrogenic environment in stress. J Endocrinol. J Endocrinol. 2023 Feb 16;256(3):e220335. doi: 10.1530/JOE-22-0335.
11. Fu L, Adu-Amankwaah J, Sang L, Tang Z, Gong Z, Zhang X, Li T, Sun H*. Gender differences in GRK2 in cardiovascular diseases and its interactions with estrogen. Am J Physiol Cell Physiol. 2023 Feb 1;324(2):C505-C516. doi: 10.1152/ajpcell.00407.2022. Epub 2023 Jan 9.
12. Tan R, You Q, Cui J, Wang M, Song N, An K, Lin L, Adu-Amankwaah J, Yuan J, Sun H*. Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38. Phytomedicine. 2023 Jan;109:154590. doi: 10.1016/j.phymed.2022.154590. Epub 2022 Dec 5.
13. Wu J, Li K, Liu Y, Feng A, Liu C, Adu-Amankwaah J, Ji M, Ma Y, Hao Y, Bu H, Sun H*. Daidzein ameliorates doxorubicin-induced cardiac injury by inhibiting autophagy and apoptosis in rats. Food Funct. 2023 Jan 23;14(2):934-945. doi: 10.1039/d2fo03416f.
14. Adu-Amankwaah J, Adzika GK, Adekunle AO, Ndzie Noah ML, Mprah R, Bushi A, Akhter N, Huang F, Xu Y, Adzraku SY, Nadeem I, Sun H*.ADAM17, A Key Player of Cardiac Inflammation and Fibrosis in Heart Failure Development During Chronic Catecholamine Stress. Front Cell Dev Biol. 2021 Dec 13;9:732952. doi: 10.3389/fcell.2021.732952. eCollection 2021.
15. Adzika GK, Hou H, Adekunle AO, Rizvi R, Adu-Amankwaah J, Shang W, Li K, Deng QM, Mprah R, Ndzie Noah ML, Sun H*. Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling. Front Cardiovasc Med. 2021 Nov 25;8:719805. doi: 10.3389/fcvm.2021.719805. eCollection 2021. PMID: 34901202.
16. Adekunle AO, Adzika GK, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Rizvi R, Akhter N, Sun H*. Predominance of Heart Failure With Preserved Ejection Fraction in Postmenopausal Women: Intra- and Extra-Cardiomyocyte Maladaptive Alterations Scaffolded by Estrogen Deficiency. Front Cell Dev Biol. 2021 Sep 29;9:685996. doi: 10.3389/fcell.2021.685996. eCollection 2021.
17. Hou HJ, Adzika GK, Qi Wu Q, Ma TT, Ma YH, Geng J, Shi MJ, Fu L, Rizvi R, Gong Z and Sun H* . Estrogen Attenuates Chronic Stress-Induced. Cardiomyopathy by Adaptively Regulating Macrophage Polarizations via b2-Adrenergic Receptor Modulation. Front Cell Dev Biol., 2021; 9, doi: 10.3389/fcell.2021.737003.
18.Adzika GK, Hou HJ, Adekunle AO, Rizvi R, Adzraku SY, Li KX, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, WK, Ma TT, Koda S, Ma XL, Sun H*. Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses. Front Cell Dev Biol, 2021;9, doi: 10.3389/fcell.2021.719351.
19. Gong Z, Li W, Bu H, He M, Hou H, Ma T, Hu X, Fu L, Adu-Amankwaah J, Sun H*.Impact of COVID-19 pandemic on the professional intention of medical and related students. BMC Med Educ. 2021 Sep 9;21(1):484. doi: 10.1186/s12909-021-02922-2.
20. Zhang L, Li C, Yang L, Adzika GK, Machuki JO, Shi M, Sun Q, Sun H*.Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress. Front Cardiovasc Med. 2021 Jun 16;8:679240. doi: 10.3389/fcvm.2021.679240. eCollection 2021.
21. Adu-Amankwaah J, Adzika GK, Adekunle AO, Ndzie Noah ML, Mprah R, Bushi A, Akhter N, Xu Y, Huang F, Chatambarara B, Sun H*. The Synergy of ADAM17-Induced Myocardial Inflammation and Metabolic Lipids Dysregulation During Acute Stress: New Pathophysiologic Insights Into Takotsubo Cardiomyopathy. Front Cardiovasc Med. 2021 Jun 4;8:696413. doi: 10.3389/fcvm.2021.696413. eCollection 2021.(review)
22. Fu L, Zhang H, Ong'achwa Machuki J, Zhang T, Han L, Sang L, Wu L, Zhao Z, James Turley M, Hu X, Hou H, Li D, E Harding S, Sun H*. GPER mediates estrogen cardioprotection against epinephrine-induced stress. J Endocrinol. 2021 May 20;249(3):209-222. doi: 10.1530/JOE-20-0451.
23.Fu L, Zhang H, Machuki JO, Zhang T, Han L, Sang L, Wu L, Zhao Z, Turley MJ, Hu X, Hou H, Li D, Harding SE, Sun H. Reply to: Estrogens for protection from an index and recurrent episodes of takotsubo syndrome? J Endocrinol. 2021;250(3):L3. doi: 10.1530/JOE-21-0227.
24. Ndzie Noah ML, Adzika GK, Mprah R, Adekunle AO, Adu-Amankwaah J, Sun H*.Sex-Gender Disparities in Cardiovascular Diseases: The Effects of Estrogen on eNOS, Lipid Profile, and NFATs During Catecholamine Stress. Front Cardiovasc Med. 2021 Feb 12;8:639946. doi: 10.3389/fcvm.2021.639946. eCollection 2021. (review)
25. Akhter N, Sun H*, Machuki JO, Ren HQ*.Protective Effect of Calcium Dobesilate on Induced AKI in Severely Burned Mice. Nephron. 2021 Jun 14:1-15. doi: 10.1159/000515420.
26. Liu X, Zhou F, Wang W, Chen G, Zhang Q, Lv R, Zhao Z, Li X, Yu Q, Meves JM, Hua H, Li X, Wang X, Sun H, Gao D. IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis. J Neuroinflammation. 2021 May 11;18(1):108. doi: 10.1186/s 12974 -021-02156-5.
27. Adu-Amankwaah J, Mprah R, Adekunle AO, Ndzie Noah ML, Adzika GK, Machuki JO, Sun H*. The cardiovascular aspect of COVID-19. Ann Med. 2021 Dec;53(1):227-236. doi: 10.1080/07853890.2020.1861644. PMID: 33345626.
28. Li W, Gillies R, He M, Wu C, Liu S, Gong Z, Sun H*. Barriers and facilitators to online medical and nursing education during the COVID-19 pandemic: perspectives from international students from low- and middle-income countries and their teaching staff. Hum Resour Health. 2021 May 12;19(1):64. doi: 10.1186/s12960-021-00609-9.
29. Lu W, Cai H, Chen Y, Liao X, Zhang L, Ma T, Sun H, Qi Y. Ghrelin inhibited pressure overload-induced cardiac hypertrophy by promoting autophagy via CaMKK/AMPK signaling pathway. Peptides. 2020 Nov 13:170446. doi: 10.1016/j.peptides.2020.170446.
30. Li W, Liu C, Liu S, Zhang X, Shi RG, Jiang H, Ling Y, Sun H*. Perceptions of education quality and influence of language barrier: graduation survey of international medical students at four universities in China. BMC Med Educ 2020 Nov 7;20(1):410. doi: 10.1186/s12909-020-02340-w.
31. Jiao L, Machuki JO, Wu Q, Shi M, Fu L, Adekunle AO, Tao X, Xu C, Hu X, Yin Z, Sun H*. Estrogen and Calcium Handing Proteins: New Discoveries and Mechanisms in Cardiovascular Diseases. Am J Physiol Heart Circ Physiol. 2020; 318(4):H820-H829. doi: 10.1152/ajpheart.00734.2019.
32. Gao L, Feng A, Li C, Schmull S, Sun H*. Decellularized Aortic Scaffold Alleviates H2O2-Induced Inflammation and Apoptosis in CD34+ Progenitor Cells While Driving Neovasculogenesis. Biomed Res Int.2020:6782072. doi: 10.1155/2020/6782072. eCollection 2020.
33. Li W, Sun H*. Migration intentions of Asian and African medical students educated in China: a cross-sectional study. Hum Resour Health. 2019;17(1):88.
34. Zhang Y, Wang Y, Yanni J, Qureshi MA, Logantha SJRJ, Kassab S, Boyett MR, Gardiner NJ, Sun H, Howarth FC, Dobrzynski H*. Electrical Conduction System Remodeling in Streptozotocin-Induced Diabetes Mellitus Rat Heart. Front Physiol. 2019 Jul 8;10:826. doi: 10.3389/fphys.2019.00826. eCollection 2019.
35. Adzika GK, Machuki JO, Shang W, Hou H, Ma T, Wu L, Geng J, Hu X, Ma X, Sun H*. Pathological cardiac hypertrophy: the synergy of adenylyl cyclases inhibition in cardiac and immune cells during chronic catecholamine stress. J Mol Med (Berl). 2019 Jul;97(7):897-907. doi: 10.1007/s00109-019-01790-0. Epub 2019 May 6. Review.
36. Machuki JO, Zhang HY, Geng J, Fu L, Adzika GK, Wu L, Shang W, Wu J, Kexue L, Zhao Z, Sun H*. Estrogen regulation of cardiac cAMP-L-type Ca2+ channel pathway modulates sex differences in basal contraction and responses to β2AR-mediated stress in left ventricular apical myocytes. Cell Commun Signal. 2019 Apr 15;17(1):34. doi: 10.1186/s12964-019-0346-2.
37. Gao L, Shi T, Wang Z, Lv J, Schmull S, Sun H*. A novel human-derived tissue-engineered patch for vascular reconstruction; Am J Transl Res. 2019;11(5):3018-3028. eCollection 2019.
38. Hou H, Zhao Z, Machuki JO, Zhang L, Zhang Y, Fu L, Wu J, Liu Y, Harding SE, Sun H*. Estrogen deficiency compromised the β2AR-Gs/Gi coupling: implications for arrhythmia and cardiac injury. Pflugers Arch. 2018;470(3):559-570. doi: 10.1007/s00424-017-2098-4.
39. Liu X, Zhang Q, Wang W, Zuo D, Wang J, Zhou F, Niu L, Li X, Qin S, Kou Y, Kong F, Pan W, Wang Y, Gao D, Sun H, Meves JM, Zheng K, Tang R. Analysis of Long Noncoding RNA and mRNA Expression Profiles in IL-9-Activated Astrocytes and EAE Mice. Cell Physiol Biochem. 2018;45(5):1986-1998. doi: 10.1159/000487975.
40. Machuki JO, Zhang HY, Harding SE, Sun H*. Molecular pathways of oestrogen receptors and β-adrenergic receptors in cardiac cells: Recognition of their similarities, interactions and therapeutic value. Acta Physiol (Oxf). 2018 Feb;222(2). doi: 10.1111/apha.12978..
41. Yan X, Wu H, Wu Z, Hua F, Liang D, Sun H, Yang Y, Huang D, Bian JS. The New Synthetic H2S-Releasing SDSS Protects MC3T3-E1 Osteoblasts against H2O2-Induced Apoptosis by Suppressing Oxidative Stress, Inhibiting MAPKs, and Activating the PI3K/Akt Pathway. Front Pharmacol. 2017 Jan 20;8:07. doi: 10.3389/fphar.2017.00007. eCollection 2017.
42. Fu L, Liu Y, Wang J, Sun Y, Zhang L, Wu T, Li Y, Wang B, Huang S, Bu H, Sun H*. Cardioprotection by low-dose of estrogen and testosterone at the physiological ratio on OVX rats during ischemia/reperfusion injury. J Cardiovasc Pharmacol. 2017；70(2):87-93. doi: 10.1097/FJC.0000000000000497. (SCI:2.227)
43. Zhang RQ, Li DY*, Xu TD, Zhu SS, Pan HJ, Fang F, Wu X, Sun H*. Antioxidative effect of luteolin pretreatment on simulated ischemia/reperfusion injury in cardiomyocyte and perfused rat heart. Chin J Integr Med. 2017 Jul;23(7):518-527. doi: 10.1007/s11655-015-2296-x. （SCI:1. 234）
44. Chong JM, Hou HJ, Zhang Y, Cao XC, Fu L, Han YT, Sang LL, Sian E Harding, Pan XH, Sun H*. Stress cardiomyopathy was prone to occur in patients with chronic diseases: Maybe a good thing. Cardiovascular Pharmacology: Open Access. 2016; 5(174):1-5. doi.org/10.4173/2329-6607.1000174.
45. Cao X, Zhou C, Chong J, Fu L, Zhang L, Sun D, Hou H, Zhang Y, Li D, Sun H*. Estrogen resisted stress-induced cardiomyopathy through increasing the activity of β₂AR-Gαs signal pathway in female rats. Int J Cardiol. 2015;187:377-86. doi:10.1016/j.international card.2015.02.113. (SCI:4.638)
46. Bao L, Lu F, Chen H, Min Q, Chen X, Song Y, Zhao B, Bu H, Sun H*. High concentration of epigallocatechin-3-gallate increased the incidences of arrhythmia and diastolic dysfunction via β2-adrenoceptor. J Food Sci. 2015; 80(3):T659-63. doi: 10.1111/1750-3841.12803. (SCI:1.649)
47. Sun Y, Wang Y, Zhang L, Xu C, Liu Y, Kang S, Yan C, Li D, Sun H*. Prevention of cardiac events caused by surgical stress in aged rats: Simultaneously activating β2-adrenoceptor and inhibiting β1-adrenoceptor. Stress. 2014; 7(4):373-81. doi: 10.3109/ 0253890.2014.915392.
48. Wu X, Xu T, Li D*, Zhu S, Chen Q, Hu W, Pan D, Zhu H, Sun H*. ERK/PP1a /PLB /SERCA2a and JNK pathways are involved in luteolin-mediated protection of rat hearts and cardiomyocytes following schemia/reperfusion. PLoS One. 2013;8(12):e82957. doi: 10.1371.
49. Kang S, Liu Y, Sun D, Zhou C, Liu A, Xu C, Hao Y, Li D*, Yan C, Sun H*. Chronic activation of the G Protein-Coupled Receptor 30 with agonist G-1 attenuates heart failure. Plos One. 2012;7(10):e48185.
50. Jiang X, Xu C, Wang Y, Gao L, Yan C, Li D, Sun H*. β(2)-Adrenoceptor transfection enhances contractile reserve of isolated rat ventricular myocytes exposed to chronic isoprenaline stimulation by improving β(1)-adrenoceptor responsiveness. J Recept Signal Transduct Res. 2012;32(1):36-41.1.
51. Liu A, Gao L, Kang S, Liu Y, Xu C, Sun H*, Li D, Yan C. Testosterone enhances estradiol's cardioprotection in ovariectomized rats J Endocrinol. 2012 ; 212(1):61-69.
52. Paur H, Wright PT, Sikkel MB, Tranter MH, Mansfield C, O'Gara P, Stuckey DJ, Nikolaev VO, Diakonov I, Pannell L, Gong H, Sun H, Peters NS, Petrou M, Zheng Z, Gorelik J, Lyon AR, Harding SE . High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi-Dependent Manner: A New Model of Takotsubo Cardiomyopathy. Circulation. 2012;126(6):697-706.
53. Jiang X, Gao L, Zhang Y, Wang G, Liu Y, Yan C, Sun H*. A comparison of the effects of ketamine, chloral hydrate and pentobarbital sodium anesthesia on isolated rat hearts and cardiomyocytes. J Cardiovasc Med (Hagerstown). 2011;12(10):732-5.
54.Fang F, Li D, Pan H, Chen D, Qi L, Zhang R, Sun H. Luteolin Inhibits Apoptosis and Improves Cardiomyocyte Contractile Function through the PI3K/Akt Pathway in Simulated Ischemia/Reperfusion. Pharmacology. 2011;88(3-4):149-58.
55. Pan H, Li D, Fang F, Chen D, Qi L, Zhang R, Xu T, Sun H*. Salvianolic Acid a demonstrates cardioprotective effects in rat hearts and cardiomyocytes after ischemia/reperfusion injury. J Cardiovasc Pharmacol. 2011;58(5):535-42.
56. Qi L, Pan H, Li D* Fang F, Chen D, Sun H*. Luteolin improves contractile function and attenuates apoptosis following ischemia-reperfusion in adult rat cardiomyocytes. Eur J Pharmacol. 2011;668(1-2):201-7.
57. Qiao WL, Wang GM, Shi Y, Wu JX, Qi YJ, Zhang JF, Sun H, Yan CD. Differential expression of Bcl-2 and Bax during gastric ischemia-reperfusion of rats. World J Gastroenterol. 2011;17(13):1718-24.
58. Wang Y, Zhao Z, Wu Q, Hao Y, Xu C, Sun Y, Sun H*, Yan C, Li D Inhibition of central sympathetic nervous tone improves cardiomyocyte contraction by increasing the response of beta 2-adrenergic receptor in aged rats Neural Regen Res. 2011;6(14):1067-1071.
59. Xu C, Liu A, Sun H*, Sun Y, Wang G, Gao L, Hao Y, and Yan C. Beta2-adrenoceptor confers cardioprotection against hypoxia in isolated ventricular myocytes and the effects depend on estrogenic environment. Journal of Receptors and Signal Transduction. 2010，30(4): 255–261（SCI: 1.992）
60. Hao Y, Sun Y, Xu C, Jiang X, Sun H*, Wu Q, Yan C, Gu S. Improvement of contractile function in isolated cardiomyocytes from ischemia-reperfusion rats by ginkgolide B pretreatment J Cardiovasc Pharmacol. 2009;54(1):3-9.
61. Wu Q, Zhao Z, Sun H*, Hao YL, Yan CD, Gu SL. Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia-reperfusion. Exp Physiol. 2008, 93(9):1034-1043.
62. Sun H, Zhou F, Wang Y, Zhang Y, Chang AM, Chen Q. Effects of beta-adrenoceptors overexpression on cell survival are mediated by Bax/Bcl-2 pathway in rat cardiac myocardial. Pharmacology. 2006, 78(2):98-104.
63. Gong H, Sun H, Koch WJ, Rau T, Eschenhagen T, Ravens U, Heubach JF, Adamson DL, Harding SE. Specific beta(2)AR blocker ICI 118,551 actively decreases contraction through a G(i)-coupled form of the beta(2)AR in myocytes from failing human heart Circulation 2002 105(21) 2497-503.
Articles in Chinese:
1. Wang Shuo, Wu Di, Liu Lei, Cui Jie, Qiao Weili, Sun Hong, Yan Changdong. Danshensu via SIRT1-SOD pathway retard aging rat aortic endothelial cells. ActaPhysiologica Sinica. 2014,05:575-582.
2. Li Li Li, Zhou Chunle, Fu Lu, Jing Jing min, Zhang Lin, Sun Hong*, estrogen to alleviate the myocardial injury induced by isoproterenol in rats by adjusting the G alpha _s-cAMP pathway. ActaPhysiologica Sinica. 2014,05:583-588.
3. Pan Chen, Liu Ying, Sun Hong, Cai Hongxing. Discussion on the training model of medical students' international perspective in China . Northwest Medical Education, 2014,04:634-636+644.
4. Hu Xiaoqin, Wang Zhirong, Zhang Zhuoqi, Sun Hong, Zhang Chaoqun, Cheng moon. Three. Effects of alcohol on the rapid atrial stimulation of oxidative stress in rabbit. Chinese Journal of Cardiac Pacing and Electrophysiology, 2014,01:50-54.
5. Gao LIping, Kang Shoulei, Sun Hong*. The protective effect of chronic estrogen receptor GPR30 on heart failure in rats. Jiangsu Medicine. 2013,22:2671-2673.
6. Sun Hong, Gao Ping, bu Hui Min, Dong Wei, Li Li Li, et al. Experimental teaching reform and effect of functional experiment center of Chinese Academy of Sciences. Chinese Journal of pathophysiology, 2013,10:1915.
7. Zhang Yang, Sun Hong, Wang Hongjun, Xu Ming, Meng Jing. The protective effect of estrogen on isoproterenol induced myocardial injury in rats. Chinese Medical Frontiers, 2013,19:20-23.
8. Gao Ping, Liu Ying, Sun Hong*. The effect of exhaustive exercise on myocardial cell contraction mediated by beta adrenergic receptor in rats. Chinese Journal of Applied Physiology, 2013,05:437-440.
9. Gao Liping, Wang Guangming, Shi Yue, Sun Hong. To explore the bilingual teaching of physiology introduction case-based learning. Continuing Medical Education, 2013,08:55-56.
10. Hao Yanling, Yuan Fenggang, Sun Hong, et al., Wang Tingting, et al., Tang L, Liu, et al. Effects of ginkgolide A on cardiac function in rats with ischemia / reperfusion injury. Chinese Pharmacological Bulletin, 2013,04:577-581.
11. Zou Jihe, Qiao Weili, Wang Guangming, Ma Hongji, Sun Hong, Yan Qi Youjian, Changdong. Exogenous H_2S reduces gastric mucosal injury induced by gastric ischemia-reperfusion in rats by activating K_ (ATP) channel. ActaPhysiologica Sinica. 2012,01:27-32.
12. Liu Yonglin, Zhang Chengbiao,Sun Hong, Gao Li, Gao Ping, et al. Study on the effect of Ginkgolides on arterial blood pressure in rats. Shanxi Traditional Chinese Medicine , 2011,04:491-492.
13. Ma Hongji, Sun Hong, Yan Changdong, et al. Investigation and analysis of bilingual teaching of physiology. Science and Technology Innovation Herald, 2011,08:160-161.
14. Bu Hui Min, Wang Meiling, Sun Hong, Zhou Zhaonian, Zhang wing. The protective effect of myocardial heat shock protein on chronic intermittent hypobaric hypoxia in developing rats. Chinese Pharmacological Bulletin, 2011,01:49-53.
15. Wu Qin, Sun Hong, Yang Liucai, Qian Chunye, Tang Chenghe, Hao Ling, Tian Jun, Xu Hongtao. Effect of caloric restriction on recovery of ischemic preconditioning in aged rats by AMPK pathway [J]. Chinese Journal of Gerontology, 2011,01:77-80.
16. Wang Ying, Zhou Feng, Sun Hong*, An increase in the expression of beta -1- adrenergic receptor fails to protect isoproterenol induced injury in rat cardiac myocytes. ActaPhysiologica Sinica. 2010,06:505-510.
17. Xu Chuanying, Sun Yiwei, Sun Hong. Perioperative use of beta -1-AR blockers and beta -2-AR agonists in elderly patients with myocardial protection. Chinese Journal of pathophysiology, 2010,10:1958.
18. Sun Hong. The reform and practice on function experiment teaching. Researches in medical education, 2010,02:245-247.
19. Wu Qin, Zhao Zhi, Sun Hong*, Zhang Yang. Hao Yanling, et al. Protective effects of estrogen on ischemia reperfusion injury in isolated rat hearts. Chinese Journal of Applied Physiology, 2009,03:355-360.
20. Wu Qin, Zhao Zhi, Sun Hong*, et al. Ischemic preconditioning protects myocardial cells from contraction by beta-2-AR.ActaPhysiologica Sinica. 2008,03:327-332.
21. Zhao Zhi, Wu Qin, Sun Hong*, Zhang Yang, et al. Effects of central sympathetic nerve activity inhibition on myocardial contractile function in aged rats. Chinese Journal of geriatric cardiovascular and cerebrovascular diseases, 2008,02:125-127.
22. Wu Qin, Sun Hong*. The protective effect of estrogen on ischemic heart disease. Advances in cardiovascular diseases, 2008,01:81-84.
23. Wang Ying, Hao Yanling, Sun Yiwei, Sun Hong*. Study on the effect of Ginsenoside on the contractile function of adult rat myocardial cells. Acta Academiae Medicinae Xuzhou. 2008,01:19-21.
24. Zhou Feng, Wang Ying, Sun Hong*. Isolation of adult rat cardiomyocytes. Science and Technology Information (Academic Research), 2008,03:104-105+107.
25. Liu Yonglin, Li Baomin,Sun Hong, Zhao Zhi, Gao Li Ping, et al. Effects of Ginkgolides on cardiovascular function in rats. Chinese Journal of Practical Medicine, 2007,36:81-82.
26. Jiang Xinwei, Sun Hong*, Zhou Jie. The effect of local anesthetics on the excitability of the sciatic nerve of toad. Acta Academiae Medicinae Xuzhou. 2007,12:797-799.
27. Li Baomin, Song Yabing, Lv Jianan, Liu Yonglin, Yuan Yuan,Sun Hong, Zong Zhimin, Xiao Hongbin. Study on Extraction and separation technology of ginkgolide. Chemical Journal, 2007,12:21-24.
28. Sun Hong, Zhao Zhi, Wu Qin, Zhang Yang, Liu Yonglin, Hao Yanling, Yan Changdong. The changes of isoproterenol in response to Gi α-2 expression in cardiomyocytes. Science and Technology Innovation Herald, 2007,36:143-144.
29. Sun Hong, Gao Liping, Qiao Weili, Wang Guangming, Shi Yue. Students abroad in physiology teaching practice study. Journal of Shanxi Medical University (Basic Medical Education Edition), 2007,06:638-639.
30. Sun Hong, Chang Aimin, Zhang Yang, Wang Ying, Xu Yalin, Increased beta adrenergic receptor expression on myocardial contractile function in rats with heart failure. Journal of Nanjing Medical University (NATURAL SCIENCE EDITION), 2007,12:1398-1402.
31. Dai Tijun，Sun Hong, Meng Jing, Wu Jingru, Ma Tao, Wang Dan. Improve the abilities of undergraduates through scientific research work. Chinese Journal of medical education, 2007,06:45-46.
32. Sun Hong, Chang AI, Zhang Yang, Jiang Xinwei. Effect of increased expression of beta _2 adrenergic receptor on contractile function of cardiomyocytes in rats with congestive heart failure. Chinese Journal of Applied Physiology, 2007,04:410-414.
33. Zhao Zhi, Sun Hong*. Effects of increased central nervous tension on cardiovascular system in the elderly. Advances in Physiological Sciences, 2007,04:379-382.
34. Sun Hong, Chen Qi. Cell Biological and Function Research of Scavenger Receptor Class B Type Ⅰ[J]. Medical Recapitulate, 2007,20:1534-1536.
35. Sun Hong, Jiang Xinwei, Chang AI min, Zhang Yang, et al. Effects of increased G_i and beta2AR expression on survival of rat cardiac myocytes induced by isoproterenol. Journal of Applied Physiology in China, 2007,03:274-275+337.
36. Gao Ping, Liu Yonglin, Sun Hong*. 1,6- two fructose diphosphate inhibits the intracellular calcium overload induced by interleukin -1 beta in the pancreatic beta cells. Acta Academiae Medicinae Xuzhou. 2007,08:503-506.
37. Chang Aimin, Zhang Yang, Wang Ying, Sun Hong*. The response of cardiac myocytes to Ca~ (2+) and isoproterenol in rats with congestive heart failure. Acta Academiae Medicinae Xuzhou. 2007,05:284-286.
38. Jiang Xinwei, Zhou Jie, Sun Hong*. Effects of electrical stimulation parameters on excitability of sciatic nerve. Acta Academiae Medicinae Xuzhou. 2007,03:158-160.
39. Zhang Yang, Chang Aimin, Sun Hong*. Effects of pentobarbital sodium anesthesia on isolated rat myocardial cells. Acta Academiae Medicinae Xuzhou. 2007,01:10-12.
40. Jiang Xinwei, Sun Hong*. Effects of local anesthetics on the excitability of sciatic nerve stem of toad. Acta Academiae Medicinae Xuzhou. 2007,27 (12):797-799.
41. Jiang Xinwei, Zhou Jie, Sun Hong*, et al. Effect of stimulation parameters on the action potential of sciatic nerve stem of toad. Acta Academiae Medicinae Xuzhou. 2006,06:507-509.
42. Jiang Xinwei, Zhou Jie, Sun Hong*. Effect of electrode position and distance on toad sciatic nerve action potential. Acta Academiae Medicinae Xuzhou. 2006,05:423-425.
43. Wang Ying, Sun Hong, Fan Leming, et al. Isolation and culture of adult rat cardiomyocytes. Acta Academiae Medicinae Xuzhou. 2005,05:393-396.
44. Sun Hong. The practice and exploration of the teaching of physiology in the past two years in our college. Journal of Xuzhou College of Education, 2004, 17(2): 89-90
45. Sun Hong, Yan Changdong, Wang Ying. A method for separating and cultured adult rabbit cardiomyocytes. Acta Academiae Medicinae Xuzhou. 2003,01:20-22.
46. Yan Changdong, Sun Hong, Qi Youjian. The role of NO synthase inhibitors in the inhibitory effect of dopamine on gastrointestinal propulsive motility in mice, Acta Academiae Medicinae Xuzhou 2000,04:261-264.
47. Sun Hong, Li Jiyao, Yu Ji. IL-1 beta preliminary study on the protective effect and mechanism of injury from acetaminophen cultured mouse liver cells. Chinese Journal of Gastroenterology and Hepatology, 1999,01:13-15.
48. Li Jiyao, Sun Hong, Yu Ji.IL-1 beta on acetaminophen induced liver injury in mice from the protective effect of body cells. Journal of Beijing Medical University, 1998, 30 (3):199-201.
49. Sun Hong, Li Jiyao, Yu Ji. Interleukin -1 has protective effect on liver injury induced by acetaminophen. ActaPhysiologica Sinica. 1997, 49(2) :153-159.)
50. Li Jiyao, Wang Ling, Sun Hong. The role of nitric oxide and cGMP in the protection of hepatic cells by neurotensin. ActaPhysiologica Sinica. 1997, 49 (4): 459-462.
Published Textbooks (in Chinese)
1. Chief Editor. Medical Functional Experiment， Science Press， Beijing. 01. 2024.
2. Chief Editor. Human Physiology (Third Edition). Higher Education Press, Beijing. 08. 2016.
3. Chief Editor. Study Guide of Human Physiology (Second Edition). Higher Education Press, Beijing. 08. 2016.
4. Chief Editor. Experiments of Medical Functional Science (Second edition). People’s Medical Publishing House, Beijing. 08.2016.
5. Assiociate Editor. Physiology. Higher Education Press, Beijing. 08.2015.
6. Assiociate Editor. Medical functional experiment (Third edition). Chinese Medical Science and Technology Press, Beijing. 08.2014.
7. Assiociate Editor. Medical functional experiment (Second edition). Chinese Medical Science and Technology Press, Beijing. 08.2010.
8. Assiociate Editor. Physiology. Beijing University Medical Press, Beijing. 08.2009.
9. Assiociate Editor. Medical functional experiment (First Edition). Chinese Medical Science and Technology Press, Beijing. 02.2008.
10. Assiociate Editor. Basis of Cardiac Morphology and Function. Second Military Medical University Press. Shanghai. 06.2005.
11. Assiociate Editor. Physiology. Southeast University Press. Nanjing. 06, 2005.
12. Editor. Human anatomy and physiology (Ministry of Health "11th Five-Year" planning textbook "). People's Medical Publishing House, Beijing.
13. Editor. Study Guide of Human Physiology. Second Military Medical University Press. Shanghai. 08.2003.
14. Editor. Human Physiology. Second Military Medical University Press. Shanghai. 08.2003.
Other information
Participation in important academic conferences
The 76th Annual Meeting of The Korean Physiological Society. October 31 - November 1, 2024. Korea University College of Medicine, Seoul, Korea
26th European Congress of Endocrinology 11-14 May 2024，Stockholm，Sweden
The 10th Scientific Congress Federation of Asian & Oceanian Physiological Societies (FAOPS), 2023 Daegu, Korea. (Poster)
Annual conference of Physiology Society, 2023, July, Harrogate, UK
The 9th Scientific Congress Federation of Asian & Oceanian Physiological Societies (FAOPS), 2019 Kobe, Japan. (Poster)
Joint meeting of Physiology societies of Zhejiang, Jiangsu Province and Shanghai，2017.05.Wuxi, Jiangsu Province (Oral report)
Physiology 2016, 2016.07.29-31, American Physiological Society and the Physiological Society, Dublin, Ireland
The 8th Scientific Congress Federation of Asian & Oceanian Physiological Societies (FAOPS), Nov. 22-25, 2015; Bangkok, Thailand
The 37th International Union of Physiological Sciences (IUPS) 2013, July 21-26. Birmingham, UK
The 22nd Annual Meeting of the ISHR-American Section, June 2000, Louisville, Kentucky, USA
American Heart Association Scientific sessions 2000, November 2000, New Orleans, Louisiana, USA
International Symposium on Molecular Signalling in Cardiovascular Biology, May 2000, London, UK
Shanghai, Jiangsu and Zhejiang Physiology Society Conference, 12-13, May，2017. Wuxi, Jiangsu, China
The 11th Physiology Teaching Conference of China Physiology Society 2016, July 1-3, Dalian, Liaoning, China
The 5th International Ion Channel Conference, June 25-30, 2015, Luzhou, China
The 15th World Congress of Pharmacology, July 2006, Beijing, China
21st International Congress of Physiology, October, 2002, Fujian, China
Hosted Research Grants
1. Education quality of international medical students studying in China: a study based on graduates’ preparedness for practice (2018-2020), Jiangsu Provincial Department of Education 2018SJA0960)
2. hiPSC-derived cardiomyocytes to model estrogen modulation of stress cardiomyopathy through β-adrenoreceptor signaling. Project of international (regional) collaboration and exchange in NSFC-RCUK_MRC (81461138036), 01.01.2015-31.12.2018
3. The role and mechanism: Estrogen inhibits stress cardiomyopathy through the β-adrenergic receptor-G protein signal pathway. National Natural Science Foundation of China (81370329). 01.01.2015-31.12.2018
4. Extracurricular system of international medical students studying in China (2015-2017), Xuzhou Medical University, (Xjy201531)
5. Study on the mechanism of the interaction between GDNF and estrogen in the protection of neuronal signaling pathways. National Natural Science Foundation of China (30870797). 01.01.2009-31.12.2011
6. A study on the cultivation of students’ exploring ability through the combination of classical and exploratory experiments. Xuzhou Medical College Project (Xjy0100231) 2010-2012
7. Study on the protective effect of estrogen on myocardial ischemia-reperfusion injury by beta-2 adrenergic receptor. Xuzhou Medical College Foundation. 2008-2010
8. Perioperative use of beta1-adrenergic receptor blockers and beta2-adrenergic receptor agonists in the protection of the elder myocardium. Xuzhou social development project (M08C063). 2008-2010
9. Protective effects of estrogen on myocardial injury in rats. Xuzhou social development project. No.58 2006-2007
10. Study on Extraction and function of Ginkgo biloba leaf. Xuzhou social development project No.62（Collaborative project). 2006-2007
11. Research and Practice on Bilingual Teaching of Basic Medical. Xuzhou Medical College Project. 2007-2009
12. Exploration of the teaching of English for Physiology. Xuzhou Medical College project (Xyj0304), 2002-2003
13. Effects of beta-adrenergic receptor and Gi on function and apoptosis of myocardial cells. Natural Science Foundation of Jiangsu Provincial Department of Education (02KJB310008). 2002-2005
14. Protective effects of estrogen on myocardial injury in rats. Xuzhou social development project. No.58.2006-2007
15. The study of gene therapy for heart failure. Xuzhou Medical College Research Fund (531410). 2003-2008
16. Study on the parameters of action potential of sciatic nerve produced by electrical stimulation. Xuzhou Medical College project (05xzj84). 2005-2006
17. Study on the protective effects of myocardial and hepatic injury. Natural Science Foundation of Jiangsu Provincial， Department of Education, and Xuzhou Social Development Project. 2005-2007
