Biography
Dr. LIU Ting serves as the Coordinator for International Student Programs at the Department of Pathophysiology (Xuzhou Medical University). She received her Ph.D. from Augusta University (the Medical College of Georgia) in the United States, and successively carried out post-doc research work at the University of Tennessee, Knoxville, focusing on the molecular mechanisms underlying renal pathophysiology and diabetes. Her research leverages advanced techniques, including single-molecule fluorescence resonance energy transfer (smFRET), molecular biology, genomics, and animal models, to explore critical pathways in kidney and metabolic diseases. Specifically, she investigates the role of Class III Phosphatidylinositol 3-Kinase (Pik3c3) in compensatory nephron hypertrophy and tubulointerstitial fibrosis, as well as the conformational dynamics of the glucagon receptor (GCGR) and its connection to type 2 diabetes. This work aims to identify novel therapeutic targets and drive the development of innovative treatments. She received the American Heart Association Pre-Doctoral Fellowship and have authored multiple peer-reviewed SCI publications.
Academic Awards
Dr. LIU Ting received many prestigious academic awards in the field of Nephrology. For instance,
AHA Predoctoral Fellowship -- AHA00170 (to Ting Liu) (2018.07-2020.06).
American Society of Nephrology Travel Award for Advances in Research Conference, San Diego, CA, United States, 2018.
Travel Award by School of Graduate Studies in Augusta University Sponsoring Travel Expenses for an Oral Presentation in American Society of Nephrology Kidney Week Conference, San Diego, CA in 2018, and New Orleans, LA in 2017 and Chicago, IL, United States, in 2016, respectively.
Plaque presentation to Nobel laureates Dr. Andrew Z. Fire and Dr. Bruce Beutler, inaugural Dr. G Lombard Kelly Distinguished Lecturer at the Department of Cellular Biology and Anatomy, Augusta University.
Publications
Representative publications:
1. Liu T, Yuan J, Dai C, Chen M, Jerry F, Humphreys, BD, Fulton, D, Kleven D, Fan X, Zheng D, Chen, JK: Pik3c3 Expression Profiling in the Mouse Kidney and Its Role in Proximal Tubule Cell Physiology. Am J Physiol-Cell Physiol, 2024 Oct 1;327(4):C1094-C1110.
2. Liu T, Susmita K, Hertslet G D, Lamichhane R. Single-molecule analysis reveals that a glucagon-bound extracellular domain of the glucagon receptor is dynamic, Journal of Biological Chemistry, 2023, 299(9) .
3. Liu T, Yuan J, Dai C, Xu J, Humphreys BD, Kleven DT, Chen JK: Cre/loxP approach-mediated downregulation of Pik3c3 inhibits the hypertrophic growth of renal proximal tubule cells. J of Cellular Physiology, 2020;1-16.
4. Liu T, Dai C, Xu J, Li S, Chen JK. The expression level of class III phosphatidylinositol-3 kinase controls the degree of compensatory nephron hypertrophy. Am J Physiol Renal Physiol, 2020; 318:F628-F638.
