Biogragh

LIU Xiangye received his Bachelor’s degree in Veterinary Sciences in 2006 from Shandong Agriculture University. In 2014, he earned his Ph.D. in Life Sciences from the Université Paris-Est Créteil in France. From 2014 to the present, Dr. Liu has worked as a professor in the Department of Pathogenic Biology and Immunology at Xuzhou Medical University. Dr. Liu is currently investigating the roles and mechanisms of mRNA alternative splicing in cancer immunology.

Education

2002-2006, Shandong agriculture University, Taian, China

2006-2009, Jilin University, Changchun, China

2009-2013, Université Paris-Est Créteil, Paris, France

Publications

Representative publications: 

1.Liu X*, Li T, Wang Y, Gao X, Wang F, Chen Y, Wang K, Luo W, Kong F, Kou Y, You H, Kong D, Zhang Q, Tang R. Delta-Like homolog 2 facilitates malignancy of hepatocellular carcinoma via activating egfr/pkm2 signaling pathway. Mol Carcinog. 2025 Jan;64(1):176-191.

2.Gao X, Ren X, Wang F, Ren X, Liu M, Cui G, Liu X*. Immunotherapy and drug sensitivity predictive roles of a novel prognostic model in hepatocellular carcinoma. Sci Rep. 2024 Apr 25;14(1):9509.

3.Gao X, Jiang P, Wei X, Zhang W, Zheng J, Sun S, Yao H, Liu X*, Zhang Q. Novel fusion protein PK5-RL-Gal-3C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity. BMC Cancer. 2023 Feb 15;23(1):154.

4.Liu X*, Shan W, Li T, Gao X, Kong F, You H, Kong D, Qiao S, Tang R. Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma. BMC Cancer. 2021 Nov 14;21(1):1224.

5.Liu X*, Li T, Kong D, You H, Kong F, Tang R. Prognostic implications of alcohol dehydrogenases in hepatocellular carcinoma. BMC Cancer. 2020 Dec 7;20(1):1204.

6.Liu X*, Li H, Deng H, Zheng C, Yan H, Chen Z, Bian A, Chen J, Zheng K. Glyceraldehyde-3-phosphate dehydrogenase of Babesia microti is a plasminogen- and actin-binding protein. Front Vet Sci. 2019 Jul 9;6:228.

7.Chen Z, Li H, Gao X, Bian A, Yan H, Kong D, Liu X*. Human Babesiosis in China: a systematic review. Parasitol Res. 2019 Apr;118(4):1103-1112.

8.Gao X, Liu X, Shan W, Liu Q, Wang C, Zheng J, Yao H, Tang R, Zheng J. Anti-malarial atovaquone exhibits anti-tumor effects by inducing DNA damage in hepatocellular carcinoma. Am J Cancer Res. 2018 Sep 1;8(9):1697-1711.

9.Yan H, Bian A, Gao X, Li H, Chen Z, Liu X*. Novel applications for an established antimalarial drug: tumoricidal activity of quinacrine. Future Oncol. 2018 Jun;14(15):1511-1520.

10.Liu X*, Zheng C, Gao X, Chen J, Zheng K. Complete molecular and immunoprotective characterization of Babesia microti enolase. Front Microbiol. 2017 Apr 11;8:622.