Biography

Professor WANG Hui has been a professor at the Department of Pathogenic biology and immunology since 2018. He has a PhD degree in Immunology from the University of Gothenburg, Sweden. Supported by an international postdoc grant from the Swedish Research Council (2013-2016), he did my postdoc training at the Department of Immunology, MD Anderson Cancer Center, under the supervision of world-wide renowned immunologists Dr. Dong Chen and Dr. Sun Shao-cong.

Education

University of Gothenburg, 02/2010 – 10/2012, PhD         

Nanjing University, 09/2005 – 06/2008, Master of Medicine

Nanjing University, 09/2001 – 06/2005, Bachelor of Science

Publications

Representative publications: 

1.Schäfer S, Smelik M, Sysoev O, Zhao, Eklund D, Lilja S, Gustafsson M, Heyn H, Julia A, Kovács I, Loscalzo J, Marsal S, Zhang H, Li X, Gawel D*, Wang H*, Benson M*. scDrugPrio: A framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases. Genome Med 2024. 16(1):42.

2.Lilja S, Li X, Smelik M, Lee EJ, Loscalzo J, Marthanda P, Hu L, Magnusson M, Sysoev O, Zhang H, Zhao Y, Sjöwall C, Gawel D*, Wang H*, and Benson M*. Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases. Cell Rep Med 2023;100956.

3.Li H, Tang Y, Ren J, Bai R, Hu L, Jia W, Cao Y, Hong L, Xu M, Gao S, Shi Y, Pan S, Wang L, Zheng K*, Zhao S*, and Wang H*. Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41dTomato-Cre. Front Immunol 2022; 946202. 

4.Shi Y, Xu M, Pan S, Gao S, Ren J, Bai R, Li H, He C, Zhao S, Shi Z, Yu F, Xiang Z and Wang H. Induction of the apoptosis, degranulation and IL-13 production of human basophils by butyrate and propionate via suppression of histone deacetylation. Immunology 2021;164 (2): 292-304. 

5.Zhao S, Tang Y, Hong L, Xu M, Pan S, Zhen K, Tang R, Zhai X*, Shi Z*, and Wang H*. Interleukin 2 regulates the activation of human basophils. Cytokine 2020;127: 154934. 

6.Hu H*, Wang H*, Xiao Y, Jin J, Chang J, Zou Q, Xie X, Cheng X, and Sun SC. Otud7b facilitates T-cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med 2016; 213:399-414.

7.Zhang H, Nestor C, Zhao S, Lentini A, Bohle B, Benson M*, and Wang H*. Profiling of human CD4⁺ T subsets identifies a Th2-specific non-coding RNA GATA3-AS1. J Allergy Clin Immunol 2013; 132: 1005-1008.

8.Wang H, Chavali S, Mobini R, Muraro A, Barbon F, Boldrin D, Aberg N, and Benson M. A pathway-based approach to find novel markers of local glucocorticoid treatment in intermittent allergic rhinitis. Allergy 2011;66(1):132-40.

9.Wang H, Mobini R, Fang Y, Barrenäs F, Zhang H, Xiang Z, and Benson M. Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation. Clin Exp Allergy 2010;40(8):1194-202.

10.Wang H*, Barrenäs F*, Bruhn S, Mobini R, and Benson M. Increased IFN-gamma activity in seasonal allergic rhinitis is decreased by corticosteroid treatment. J Allergy Clin Immunol 2009;124(6):1360-2.