Biography
Dr. Hui Wang is a Professor at the Department of Pathogen Biology and Immunology, Xuzhou Medical University. He received his PhD in Immunology from the University of Gothenburg in 2012. Supported by an international postdoctoral fellowship from the Swedish Research Council, he completed his postdoctoral training at MD Anderson Cancer Center under the supervision of renowned immunologists Dr. Chen Dong and Dr. Shao-Cong Sun. He is currently also a visiting scholar at Karolinska Institutet.
His research focuses on immune cell differentiation and modulation, with particular emphasis on lymphocytes and microglia. He has published over 58 SCI-indexed papers, with more than 2,100 citations and an H-index of 27. He also serves as a reviewer for international journals including Allergy and Mucosal Immunology.
Education
University of Gothenburg, 02/2010 – 10/2012, PhD
Nanjing University, 09/2005 – 06/2008, Master of Medicine
Nanjing University, 09/2001 – 06/2005, Bachelor of Science
Selected publications:
1 Yan W, Zhao Y, Li H, Hong L, Jia Q, Zhu D, Xiang D, Du L, Hu L, Bai R, Xu M, Tang Y, Chen X, Cao Y, Jia W, Wang S, Liu Y, Ren J, Pan S, Shi Y, Gao S, Dong F, Shi J, Li J, Zheng K#, Yang J#, Zhao S#, Wang H#. Aurka-Bhlhe41 axis prevents premature aging-like microglial dysfunction and promotes remyelination. Nat Commun, 2026. doi:10.1038/s41467-026-71014-w.
2 Yan W, Xiang D; Du L, Zhu D, Jia Q, Liu Y, Wang S, Liu L, Guan H, Zhao Y, Jiang G#, Gao S#, Wang H#. Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination. iScience, 2026, 29(2): (114718).
3 Zou X, Wang K, Deng Y, Guan P, Pu Q, Wang Y, Mou J, Du Y, Lou X, Wang S, Jiang N, Zhou S, Wang H, Du D, Liu X, Hu H, Zhang H. Hypoxia-inducible factor 2alpha promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism. Immunity, 2024.57:2808-2826 e2808.
4 Schäfer S, Smelik M, Sysoev O, Zhao, Eklund D, Lilja S, Gustafsson M, Heyn H, Julia A, Kovács I, Loscalzo J, Marsal S, Zhang H, Li X, Gawel D#, Wang H#, Benson M#. scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases. Genome Med, 2024. 16(1):42
5 Lilja S, Li X, Smelik M, Lee EJ, Loscalzo J, Marthanda PB, Hu L, Magnusson M, Sysoev O, Zhang H, Zhao Y, Sjowall C, Gawel D#, Wang H#, Benson M#. Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases. Cell Rep Med, 2023. 4(3):100956.
6 Chen X, Hu J, Wang Y, Lee Y, Zhao X, Lu H, Zhu G, Wang H, Jiang Y, Liu F, Chen Y, Kim BS, Zhou Q, Liu X, Wang X, Chang SH,Dong C. The FoxO4/DKK3 axis represses IFN-gamma expression by Th1 cells and limits antimicrobial immunity. J Clin Invest, 2022. 132(18).
7 Li H, Tang Y, Ren J, Bai R, Hu L, Jia W, Cao Y, Hong L, Xu M, Gao S, Shi Y, Pan S, Wang L, Zheng K#, Zhao S#, Wang H#. Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41dTomato-Cre. Front Immunol, 2022. 15:13:946202. 946202.
8 Shi Y, Xu M, Pan S, Gao S, Ren J, Bai R, Li H, He C, Zhao S, Shi Z, Yu F, Xiang Z, Wang H. Induction of the apoptosis, degranulation and IL-13 production of human basophils by butyrate and propionate via suppression of histone deacetylation. Immunology, 2021. 164(2):292-304.
9 Jie Z, Ko CJ, Wang H, Xie X, Li Y, Gu M, Zhu L, Yang JY, Gao T, Ru W, Tang SJ, Cheng X,Sun SC. Microglia promote autoimmune inflammation via the noncanonical NF-kappaB pathway. Sci Adv, 2021. 7(36):eabh0609.
10 Xie X, Zhu L, Jie Z, Li Y, Gu M, Zhou X, Wang H, Chang JH, Ko CJ, Cheng X,Sun SC. TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells. Cell Mol Immunol, 2021. 18(9):2262-2274.
