CN
WEI Yanxia
Professor
Department:
Pathogenic Biology and Immunology
Email Address:
weiyx2007@aliyun.com
Research Fields:
Gut microbiota and immunometabolism

Biography

WEI Yanxia is a young distinguished professor, doctoral supervisor, and professor in the Department of Pathogenic Biology and Immunology at Xuzhou Medical University. Currently serving as a member of the Jiangsu Society of Microbiology, a member of the Bacteriology Group of the Medical Microbiology and Immunology Special Committee of the Chinese Society of Microbiology, and the Vice Chairman of the Science Popularization Committee of the Jiangsu Society of Immunology.

She mainly engaged in research on microecology and host health and has received more than 10 research projects including National Natural Science Foundation projects, and the Major Natural Science Research Project of Jiangsu Provincial Universities. As the first or corresponding author, she has published 15 SCI-indexed papers. She served as the deputy editor-in-chief of the digital version of the textbook "Medical Microbiology" for five-year undergraduate clinical medicine majors in National Higher Education Institutions, deputy editor-in-chief of the planning textbook for medical experimental teaching in national higher education institutions, and editorial board member for four textbooks/monographs, including the English planning textbook for clinical medicine majors in national higher education institutions. More information about Prof. Dr. Wei’s publication record can be accessed via the link below:

https://orcid.org/0000-0003-2706-957X

Academic Awards

Prof. Dr. WEI Yanxia received many prestigious academic awards. For instance,

Qing Lan Project of Jiangsu Province

333 Project of Jiangsu Province

Young distinguished professor of Xuzhou Medical University

Publications

1. Representative publications:

2. Wei YX#, Peng N# , Deng C, Zhao FT, Tian J, Tang Y, Yu SL, Chen Y, Xue Y, Xiao F 1, Zhou YB, Li XM, Zou HJ, Rui K*, Lin X*, Lu LW*. Aryl hydrocarbon receptor activation drives polymorphonuclear myeloid-derived suppressor cell response and efficiently attenuates experimental Sjögren's syndrome. Cell Mol Immunol. 2022 Dec;19(12):1361-1372.

3. Wei YX*,#, Liu MN#, Han JZ, Huang HH, Xu SH, Zhang SH, Jing QY, Wang HY, Bu HM, Kou YB, Liu ZZ, Zheng KY, Wang YG*. A tyrosine catabolic intermediate 4-hydroxyphenylpyruate attenuates murine endotoxic shock by blocking NLRP3 inflammasome activation. Int Immunopharmacol. 2022,111:109098.

4. Wei YX, Zheng KY, Wang YG*. Gut microbiota-derived metabolites as key mucosal barrier modulators in obesity. World J Gastroenterol. 2021, 27(33):5555-5565.

5. Wei YX#, Gao J#, Kou YB, Liu MN, Meng LY, Zheng XP, Liang M, Sun HX, Liu ZZ, Wang YG*. The intestinal microbial metabolite desaminotyrosine is an anti-inflammatory molecule that modulates local and systemic immune homeostasis. FASEB J. 2020,34(12):16117-16128.

6. Wei YX , Gao J, Kou YB, Meng LY, Zheng XP, Liang M, Sun HX, Liu ZZ, Wang YG*. Commensal Bacteria Impact a Protozoan's Integration into the Murine Gut Microbiota in a Dietary Nutrient-Dependent Manner. Appl Environ Microbiol. 2020, 86(11):e00303-20.

7. Liu DB, Zeng LB, Yan ZH, Jia JQ, Gao J, Wei YX*. The mechanisms and safety of probiotics against toxigenic Clostridium difficile. Expert Rev Anti Infect Ther. 2020, 18(10):967-975.

8. Wei YX*,#, Gao J#, Liu DB#, Li Y, Liu WL. Adaptational changes in physiological and transcriptional responses of Bifidobacteriu longum involved in acid stress resistance after successive batch cultures. Microb Cell Fact. 2019, 12;18(1):156. IF: 6.4JCR一区)

9. Wei YX*,# ,Yang F# , Wu Q , Gao Jing, Liu WL, Liu C, Guo XK , Suwal S, Kou YB , Zhang B, Wang YG, Zheng KY* and Tang RX*. Protective Effects of Bifidobacterial Strains Against Toxigenic Clostridium difficile. Front Microbiol, 2018, 8;9:888.

10. Wei YX#, Li Y#, Yang F, Wu Q, Liu DB, Li XY, Hua H, Liu XM, Wang YG, Zheng KY and Tang RX*. Physical and functional interplay between MazF1Bif and its noncognate antitoxins from Bifidobacterium longum. Appl Environ Microbiol, 2017, 17;83(9), pii: e03232-16.

11. Wei YX#, Ye L#, Liu DB, Zhang ZY, Liu C, Guo XK*, Activation of the chromosomally encoded mazEF(Bif) locus of Bifidobacterium longum under acid stress. Int J Food Microbiol, 2015, 17(207):16-22.