Biography

2024.07--Currently, Department of Physiology, Xuzhou Medical University, Associate professor

2012.12--2016.09, 2019.06-2024.07, Department of Physiology, Xuzhou Medical University, Lecturer

2010.08--2012.12, Department of Physiology, Xuzhou Medical University, Teaching assistant

Education

2013.09--2016.07, Nanjing Medical University, Biochemistry and Molecular Biology, PhD.

2016.09--2019.06, Nanjing Medical University, Biochemistry and Molecular Biology, PhD. supervisor: Luo Gu

2007.09--2010.07, Xuzhou Medical college, Human anatomy and tissue embryology, Master, supervisor: Changdong Yan

2002.09-2007.06, Anhui University of Science and Technology, Laboratory medicine, Bachelor degree

Publications

Representative publications: 

1.Liu L, Xu H, Shi Y, Cui J, Wu J, Li S. p53 regulates the effects of DAPT on Rac1 activation and migration of non-small-cell lung cancer cells. Heliyon. 2023 Mar 2;9(3):e14169.

2.Cai C^#, Zhang M^#, Liu L^#, Zhang H, Guo Y, Lan T, Xu Y, Ma P, Li S. ADAM10-cleaved ephrin-A5 contributes to prostate cancer metastasis. Cell Death Dis. 2022 May 12;13(5):453.

3.Zhang L, Xu Y, Cai E, Zheng M, Liu L, Wang Q, Li S. TSPAN8 regulates EGFR/AKT pathway to enhance metastasis in gastric cancer. Mol Biol Rep. 2023 Oct;50(10):7955-7965.

4.Wang X, Wang Y, Wang L, Shi S, Yang C, Jiang W, Luan Z, Liu L*, Yao R*. Oligogenesis in the "oligovascular unit" involves PI3K/AKT/mTOR signaling in hypoxic-ischemic neonatal mice. Brain Res Bull. 2020 Feb;155:81-91.

5.Zhao X, Ma Y, Cui J, Zhao H, Liu L, Wang Y, Min P, Zhang L, Chen Y, Du J, Zhang Y, Gu L. FLCN Regulates HIF2α Nuclear Import and Proliferation of Clear Cell Renal Cell Carcinoma. Front Mol Biosci. 2020 Jul 28;7:121.

6.Liu L, Zhang L, Zhao S, Zhao XY, Min PX, Ma YD, Wang YY, Chen Y, Tang SJ, Zhang YJ, Du J, Gu L. Non-canonical Notch Signaling Regulates Actin Remodeling in Cell Migration by Activating PI3K/AKT/Cdc42 Pathway. Front Pharmacol. 2019 Apr 16;10:370. doi: 10.3389/fphar.2019.00370. eCollection 2019.

7.Zhang L, Liu L, Zhan S, Chen L, Wang Y, Zhang Y, Du J, Wu Y, Gu L. Arsenic Trioxide Suppressed Migration and Angiogenesis by Targeting FOXO3a in Gastric Cancer Cells. Int J Mol Sci. 2018 Nov 24;19(12):3739. doi: 10.3390/ijms19123739.

8.Liu H, Liu L, Wei Q, Cui J, Yan C, Wang X, Wu Y. Xiaokening stimulates endothelial nitric oxide release in diabetic rats. Singapore Med J. 2015 Jul;56(7):401-6. doi: 10.11622/smedj.2015111.

9.Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells.

10.Zheng M, Qiao W, Cui J, Liu L, Liu H, Wang Z, Yan C.Mol Cell Biochem. 2014 Aug;393(1-2):59-67. doi: 10.1007/s11010-014-2046-y. Epub 2014 Apr 13.

11.Liu L, Liu Y, Cui J, Liu H, Liu YB, Qiao WL, Sun H, Yan CD. Oxidative stress induces gastric submucosal arteriolar dysfunction in the elderly. World J Gastroenterol. 2013 Dec 28;19(48):9439-46.

12.Liu L, Cui J, Song CJ, Bian JS, Sparatore A, Soldato PD, Wang XY, Yan CD. H(2)S-releasing aspirin protects against aspirin-induced gastric injury via reducing oxidative stress. PLoS One. 2012;7(9):e46301.

13.Liu L, Liu H, Sun D, Qiao W, Qi Y, Sun H, Yan C. Effects of H₂S on myogenic responses in rat cerebral arterioles. Circ J. 2012;76(4):1012-9.