Biography
Prof. Dr. LIU Xiaomei serves as the Immunology Discipline Leader of Xuzhou Medical University. She received her Ph.D. diploma from Nanjing Medical University, and as a senior visiting scholar, she conducted research on "Mechanisms of astrocytes in spinal cord injury and repair" at the Department of Neuroscience, University of California, San Diego, from October 2017 to November 2018. She has published over 30 SCI papers, including were published in journals such as GLIA, J Neuroinflammation, J Biol Chem, and J Pathol. In the study of the pathological mechanism of multiple sclerosis, she ever got the funding of 9 general projects, including National Natural Science Foundation of China, the natural science foundation of Jiangsu Province, etc.
More information about Prof. Dr.Liu’s publication record can be accessed via the link below:
https://orcid.org/0000-0002-7330-262X
Academic Awards
Prof. Dr. LIU Xiaomei received many academic awards in the field of Neuroimmunology. For instance,
The Second Prize of the Natural Science Award from the Ministry of Education
The First Prize of Huaihai Science and Technology Award
The Third Prize of Jiangsu Medical Science and Technology Award.
The Third prize of natural science excellent academic paper of Xuzhou
More information about Prof. Dr. Liu’s research group can be accessed via the link below:
https://www.x-mol.com/groups/wang_wenshi?lang=zh
Publications
Representative publications:
1.SAG, a sonic hedgehog signaling agonist, alleviates anxiety behavior in high-fat diet-fed mice. Dexu Sun, Jiaxin Deng, Yifan Wang, Jinyu Xie, Xiaocui Li, Xiangyang Li, Xiaotian Wang, Feng Zhou, Suping Qin*, Xiaomei Liu*. Brain Res Bull，2023; 195:25-36.
2.Qingxiu Zhang#, Ying Yang#, Yingyu Chen#, Yifan Wang, Suping Qin, Ruixue Lv, Menglu Zhou, Qian Yu, Xiangyang Li, Xiaocui Li, Xiaotian Wang, Hongjuan You, Yugang Wang, Feng Zhou*, Xiaomei Liu*. The LncRNA AK018453 regulates TRAP1/Smad signaling in IL-17-activated astrocytes: A potential role in EAE pathogenesis. Glia, 2022; 70(11):2079-2092.
3.Xiaomei Liu#*,Feng Zhou#, Weixiao Wang#, Guofang Chen, Qingxiu Zhang, Ruixue Lv, Zijun Zhao, Xiangyang Li, Qian Yu, Jessica M. Meves, Hui Hua, Xiaocui Li, Xiaotian Wang, Hong Sun, Dianshuai Gao*. IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis. J Neuroinflammation, 2021, 18(1):108
4.Xiaomei Liu#, Feng Zhou#, Ying Yang, Weixiao Wang, Liping Niu, Dongjiao Zuo, Xiangyang Li, Hui Hua, Bo Zhang, Yanbo Kou, Jingjing Guo, Fanyun Kong, Wei Pan, Dianshuai Gao, Jessica M. Meves, Hong Sun, Min Xue, Qingxiu Zhang, Yingwei Wang*, Renxian Tang*. MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling. Glia. 2019; 67(1) :101-112.
5.Feng Zhou#*, Xiaomei Liu#, Lin Gao#, Xinxin Zhou#, Qianwen Cao, Liping Niu, Jing Wang, Dongjiao Zuo, Xiangyang Li, Ying Yang, Minmin Hu, Yinghua Yu, Renxian Tang, Bong Ho Lee, Byoung Wook Choi, Yugang Wang, Yoshihiro Izumiya, Min Xue, Kuiyang Zheng and Dianshuai Gao*. HIV-1 Tat enhances purinergic P2Y4 receptor signaling to mediate inflammatory cytokine production and neuronal damage via PI3K/Akt and ERK MAPK pathways, J Neuroinflammation, 2019, 16(1):71 (IF:9.3)
6.Xiaomei Liu, Qing Zhang, Weixiao Wang, Dongjiao Zuo, Jing Wang, Feng Zhou, Liping Niu, Xiangyang Li, Suping Qin, Yanbo Kou, Fanyun Kong, Wei Pan, Yugang Wang, Dianshuai Gao, Hong Sun, Jessica M. Meves, Kuiyang Zheng*, Renxian Tang*, Analysis of Long Noncoding RNA and mRNA Expression Profiles in IL-9-activated Astrocytes and EAE Mice, Cell Physiol Biochem. 2018; 45:1986-1998.
7.Feng Zhou#, Xiaomei Liu #, Dongjiao Zu#, Min Xue#, Lin Gao, Ying Yang, Jing Wang, Liping Niu, Qianwen Cao, Xiangyang Li, Hui Hua, Bo Zhang, Minmin Hu, Dianshuai Gao, Kuiyang Zheng, Yoshihiro Izumiya and Renxian Tang, HIV-1 Nef-induced lncRNA AK006025 regulates CXCL9/10/11 cluster gene expression in astrocytes through interaction with CBP/P300, J Neuroinflammation, 2018, 5(1) :303
8.Suping Qin, Dexu Sun, Hui Li, Xiangyang Li, Wei Pan, Chao Yan, Renxian Tang*, and Xiaomei Liu*. The Effect of SHH-Gli Signaling Pathway on the Synovial Fibroblast Proliferation in Rheumatoid Arthritis, Inflammation, 2016, 39(2): 503-512.
9.Xiaomei Liu, Fengxia He, Rongrong Pang, Dan Zhao, Wen Qiu, Kai Shan, Jing Zhang, Yanlai Lu, Yan Li, Yingwei Wang*, Interleukin-17 (IL-17)-induced MicroRNA 873 (miR-873) Contributes to the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting A20, Ubiquitin-editing Enzyme, J Biol Chem, 2014, 289(42): 28971-28986.
10. Xiaomei Liu, Dongsheng Pei, Qiuhua Guan, Yafeng Sun, Xiaotian Wang, Qingxiu Zhang, Guangyi Zhang*, Neuroprotection of Tat-GluR6-9c against Neuronal Death Induced by Kainate in Rat Hippocampus via Nuclear and Non-nuclear Pathways, J Biol Chem, 2006, 281(25): 17432-17445 (IF: 5.8).
