Biography

Research Focus: Mechanisms of epigenetic regulation in cancer; Bioinformatics.

After earning a Ph.D. from Tsinghua University in January 2011, Prof. Zhang pursued postdoctoral research at the Stowers Institute for Medical Research in the United States and later at Pennsylvania State University. Prof. Zhang joined the faculty of Xuzhou Medical University in 2015. In recent years, Prof. Zhang has published multiple research papers as the first author or corresponding author in leading international journals such as PNAS. Prof. Zhang has also received several research grants from the National Natural Science Foundation of China (General Program) and the Jiangsu Provincial Natural Science Foundation (Young Scientists Program). More information about Prof. Zhang’s publication record can be accessed via the link below:

https://orcid.org/0000-0002-2516-4963

Publications

Representative publications:

1.Zhang, Daoyong; Bai, Lu*. Interallelic interaction and gene regulation in budding yeast. PNAS. 2016, 113(16):4428-33.

2.Sun Z, Wang Z, Zhang Y, Li X, Zhou H, Shao S, Cao H, Liu H*, Zhang D*. SMARCC2 silencing suppresses oncogenic activation through modulation of chromatin accessibility in breast cancer. Biochem Biophys Res Commun. 2024 Sep 10:724:150223.

3.Sun JM, Fan HY, Zhu Y, Pan TT, Wu YP, Zhang DY*, Hou XY*. Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration. Life Sci Alliance. 2023 Sep 21;6(12):e202301966.

4.Wu C, Xia D, Wang D, Wang S, Sun Z, Xu B, Zhang D*. TCOF1 coordinates oncogenic activation and rRNA production and promotes tumorigenesis in HCC. Cancer Sci. 2022 Feb;113(2):553-564.

5.Sun Z, Zhou D, Yang J*, Zhang D*. Doxorubicin promotes breast cancer cell migration and invasion via DCAF13. FEBS Open Bio. 2022 Jan;12(1):221-230.

6.Wang S, Xia D, Wang X, Cao H, Wu C, Sun Z, Zhang D*, Liu H*. C/EBPβ regulates the JAK/STAT signaling pathway in triple-negative breast cancer. FEBS Open Bio. 2021 Apr;11(4):1250-1258.

7.Shao S, Cao H, Wang Z, Wu C, Wang S, Zhang D*.  CHD4/NuRD complex regulates complement gene expression and correlates with CD8 T cell infiltration in human hepatocellular carcinoma. Clin Epigenetics. 2020 Feb 18;12(1):31.

8.Cao H, Chu X, Wang Z, Guo C, Shao S, Xiao J, Zheng J*, Zhang D*. High FOXK1 expression correlates with poor outcomes in hepatocellular carcinoma and regulates stemness of hepatocellular carcinoma cells. Life Sciences. 2019, 228:128-134.