Biography

Dr. Chen Renjin is an Associate Professor and Master’s Supervisor. He serves as the Director of the Department of Medical Experimental Animal Science, Director of the Comprehensive Biology Teaching Laboratory, Head of the Zoology Discipline, Head of the Transgenic Experiment Platform, and Head of the Humanized Mouse Platform. He also serves as a thesis review expert for the Ministry of Education’s Degree and Graduate Education Development Center. From September 2018 to August 2020, he was a visiting scholar in the Department of Immunology at Washington University School of Medicine in St. Louis. He has presided over or completed numerous projects, including two grants from the Natural Science Foundation of Jiangsu Province, a First-Class Grant from the China Postdoctoral Science Foundation, a major project funded by the Natural Science Foundation for Colleges and Universities in Jiangsu Province, and a Jiangsu Provincial Postdoctoral Science Foundation project. He has published over 20 SCI-indexed papers as the first or corresponding author. He has applied for four national invention patents, two of which have been granted. He also received the Third Prize for Scientific and Technological Progress in Xuzhou City (ranking first).

Under his guidance, undergraduate students have won a Bronze Award at the China International College Students’ "Internet+" Innovation and Entrepreneurship Competition; a Silver Award at the 14th "Challenge Cup" (Qin Chuang Yuan) China College Student Entrepreneurship Plan Competition; one First Prize and two Third Prizes at the National Life Science Competition (Innovation and Entrepreneurship Category); and a Third Prize at the National Life Science Competition (Scientific Inquiry Category).

Publications:

1. Shuai Yang , Jiawei Song, Zhenzhen Wang, Guang Peng , Linglin Tong , Xin Li , Kexin Yang , Yang Chen, He Zhang, Qing Zhang , Renjin Chen. eIF6 deficiency alleviates colorectal cancer by modulating the gut microbiota and related metabolites，Cell Death Differ, 2026 Jan 31.

2. He Zhang , Xiaohan Zhang , Zihan Yun , Yang Chen , Suhua Cang, Yating Shao, Erteng Jia , Renjin Chen. Loss of diurnal oscillatory rhythms in gut microbiota correlates with progression of atherosclerosis. Food Funct. 2025 May 6;16(9):3423-3438.

3. Zhenzhen Wang, Shuai Yang, Linglin Tong , Xin Li , Weiyi Mao, Honghua Yuan, Yang Chen , Shenyang Zhang , He Zhang, Renjin Chen.eIF6 deficiency regulates gut microbiota, decreases systemic inflammation, and alleviates atherosclerosis. 2024 Oct 22;9(10):e0059524

3. Shuai Yang, Linglin Tong , Xin Li #, Yuchen Zhang , Hao Chen, Wei Zhang, He Zhang , Yang Chen, Renjin Chen. A novel clinically relevant human fecal microbial transplantation model in humanized mice. Microbiol Spectr.. 2024 Aug 20:e0043624..

4. Yang Chen, Zhenzhen Wang, Xuemei Xian, Yun Zhuang, Jiajia Chang, Xiaoqiang Zhan, Xufeng Han, Quangang Chen, Zhangping Yang, Renjin Chen. Eukaryotic initiation factor 6 repression mitigates atherosclerosis progression by inhibiting macrophages expressing Fasn. IUBMB Life. 2023 May;75(5):440-452.

5. Renjin Chen , Leran Wang 2, Tammy Koch 1, Vanessa Curtis 1, Huiqing Yin-DeClue 1, Scott A Handley 3, Liang Shan 1, Michael J Holtzman 1, Mario Castro 4, Leyao Wang. Sex effects in the association between airway microbiome and asthma. Ann Allergy Asthma Immunol. 2020 Dec;125(6):652-657.

6. Renjin Chen , Zhenzhen Wang , Quangang Chen , Tengye Zhang, Yuhua Zhu, Xuemei Xian, Xufeng Han.Heme oxygenase-2 suppresses acute inflammation and improves the survival of skin allografts. Int Immunopharmacol. 2018 Oct:63:191-197.