Biography

Dr. Jin Gao is an Associate Professor at the Department of Cellular Biology and Neurobiology, Xuzhou Medical University. He received his Ph.D. in Human Anatomy and Histology from the Fourth Military Medical University in 2016. Prior to that, he obtained his Master's degree in Biochemistry and Molecular Biology and his Bachelor's degree in Clinical Medicine from Xuzhou Medical University in 2007 and 2004, respectively.From 2024 to 2025, he worked as a Visiting Scholar at the Hong Kong University of Science and Technology (HKUST), where he engaged in research on the industrialization of traditional Chinese medicine.

Her research focuses on the mechanisms of neuronal cell injury and repair in neurodegenerative diseases, as well as the therapeutic effects and underlying mechanisms of sleep apnea-hypopnea syndrome. He has led three research projects funded by the National Natural Science Foundation of China and the Jiangsu Natural Science Foundation. She has published a series of papers as first or corresponding author in peer-reviewed SCI journals, including Cell Death and Disease, and Brain Research Bulletin.

Education

Fourth Military Medical University, 09/2012 - 06/2016, Ph.D. in Human Anatomy and Histology

Xuzhou Medical University, 09/2004 - 06/2007, Master of Medicine in Biochemistry and Molecular Biology

Xuzhou Medical University, 09/1999 - 06/2004, Bachelor of Medicine in Clinical Medicine

Publications:

1. Gao J, Kang XY, Sun S, Li L, Zhang BL, Li YQ, Gao DS*. Transcription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression. Cell Death and Disease, 2016, (7): e2217. doi:10.1038/cddis.2016.120.

2. Gao J, Kang XY, Sun S, Li L, Gao DS*. MES23.5 DA immortalized neuroblastoma cells self-protect against early injury by overexpressing glial cell-derived neurotrophic factor via Akt1/Eya1/Six2 signaling. Journal of Molecular Neuroscience, 2020, 70(3): 328-339.

3. Gao J, Qin DL, Tang CX, Kang XY, Song CJ, Zhang CT*. Smarcd1 antagonizes the apoptosis of injured MES23.5 DA cells by enhancing the effect of Six2 on GDNF expression. Neuroscience Letters, 2021, 760: 136088. doi:10.1016/j.neulet.2021.136088.

4. Wang W¹, Lv ZY¹, Gao J¹, Liu MT, Wang YX, Tang CX, Xiang J*. Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation in the MPTP mouse model of Parkinson's disease. Brain Research Bulletin, 2021, (174): 349–358.

5. Zhang CT, Gao J, Zhu SY*. Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia. In Vitro Cellular & Developmental Biology - Animal, 2021, 57(10): 944-952. doi:10.1007/s11626-021-00607-0. (IF: 2.416, 4区)

6. Zhang CT, Qin DL, Cao XY, Kan JS, Huang XX, Gao DS, Gao J*. Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA Domain 1 expression. iScience, 2023, 26(7): 107049. doi:10.1016/j.isci.2023.107049.

7. Cao XY, Liu Y, Kan JS, Huang XX, Kambey PA, Zhang CT, Gao J*. Microglial SIX2 suppresses lipopolysaccharide (LPS)-induced neuroinflammation by up-regulating FXYD2 expression. Brain Research Bulletin, 2024, 212: 110970. doi:10.1016/j.brainresbull.2024.110970.

8. Kan JS, Cao XY, Ye YX, Huang XX, Sun GJ, Gao J*. SIX2-mediated microglial M2 polarization and exosomal miR-3470b delivery protect dopaminergic neurons in Parkinson's disease. CNS Neuroscience & Therapeutics, 2026, 32(2): e70756. doi:10.1002/cns.70756.

9. Zhang CT, Ye YX, Huang XX, Wei XJ, Ji L, Zhang WH, Gao J*, Chen R*. Intermittent hypoxia drives lung microbiome-metabolome remodeling to create a pro-inflammatory landscape in murine OSAHS. Frontiers in Microbiology, 2026. doi:10.3389/fmicb.2026.1797420.