Biography

Dr. Yanyan Fu is an Associate Professor at the School of Basic Medicine and Life Sciences, Xuzhou Medical University. She received her Master of Medicine in Genetics from Chongqing Medical University in 2005. Prior to that, she obtained her Bachelor of Science in Clinical Medicine from Wuhan University of Science and Technology in 2002.

Her research focuses on neuroinflammation and immunopharmacology, particularly the regulation of cognitive deficits and neuroinflammatory responses using natural compounds. She has served as Principal Investigator for one project funded by the National Natural Science Foundation of China (Youth Program) and one project funded by the Natural Science Foundation of Jiangsu Province (Youth Program). He has published over 7 SCI-indexed papers.

Education

Chongqing Medical University, 09/2002 – 07/2005, Master of Medicine (Genetics)

Wuhan University of Science and Technology, 09/1997 – 07/2002, Bachelor of Science (Clinical Medicine)

Publications:

1. Feng Z, Pan M, Liu H, Liu M, Yang J, Wang CY, Yao R^#, Liu H^#, Fu Y^#. Reelin promotes cerebral angiogenesis via mTOR/HIF-1α-mediated transcriptional upregulation of Netrin-4. Tissue Cell, 2026. doi: 10.1016/j.tice.2026.103727.

2. Pan Z, Lin H, Fu Y, Zeng F, Gu F^#, Niu G^#, Fang J^#, Gu B^#. Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer. Frontiers in Immunology, 2023, 14:1086898.

3. Song J, Li H, Wang N, Zhou X, Liu Y, Zhang Z, Feng Q, Chen Y, Liu D, Liang J, Ma X, Wen X^#, Fu Y^#. Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p. Frontiers in Pharmacology, 2022, 13:1044375.

4. Wen X, Fu Y, Liu H, Wu J, Shao X, Zhang X, Tang M, Shi Y, Ma K, Zhang F, Wang Y, Tang H, Han D, Zhang P, Wang S, Xu Z^#, Song Y^#. Neuroprotection of sevoflurane against ischemia/reperfusion induced brain injury. Molecular Neurobiology, 2016, 53(3):1661-1671.

5. Zhang F, Fu Y, Zhou X, Pan W, Shi Y, Wang M, Zhang X, Qi D, Li L, Ma K, Tang R, Zheng K, Song Y. Depression-like behaviors and heme oxygenase-1 are regulated by Lycopene in lipopolysaccharide-induced neuroinflammation. J Neuroimmunol, 2016, 298:1-8.

6. Fu Y, Liu H, Song C, Zhang F, Liu Y, Wu J, Wen X, Liang C, Ma K, Li L, Zhang X, Shao X, Sun Y, Du Y, Song Y^#. Mangiferin regulates cognitive deficits and heme oxygenase-1 induced by lipopolysaccharide in mice. International Immunopharmacology, 2015, 29(2):950-956.

7. Fu Y, Zhang F, Zhang L, Liu H, Zhao Z, Wen X, Wu J, Qi D, Sun Y, Du Y, Dong H, Liu Y#, Song Y#. Mangiferin regulates interleukin-6 and cystathionine-b-synthase in lipopolysaccharide-induced brain injury. Cellular and Molecular Neurobiology, 2014, 34(5):651-657.