CN
LI Chong
Professor, Master's Supervisor
Department:
Department of Biochemistry
Email Address:
lichong@xzhmu.edu.cn
Research Fields:
Molecular Mechanisms of Ischemic Brain Disease

Biography

Dr. Chong Li is a Professor at the Department of Biochemistry, Xuzhou Medical University. He received his PhD in Biochemistry and Molecular Biology from Chinese Academy of Sciences and completed postdoctoral training at University of Illinois. His research focuses on the molecular mechanisms and signaling pathways of cell apoptosis in brain ischemia.


Education

Chinese Academy of Sciences, 09/1999 – 07/2004, PhD        

Peking University, 09/1995 – 07/1999, Bachelor of Science


Publications:

1 Niu XQ, Li DD, Bao YJ, Yang Q, Liu YK, Lu F, Yan JZ, Yin XH, Li C. Neuroprotective effect of meglumine cyclic adenylate against ischemia/reperfusion injury via STAT3-Ser727 phosphorylation. J Stroke Cerebrovasc Dis. 2023;32(1):106892.

2 Lu F, Xu X, Yang G, Hong X, Chen L, Yin X, Yan J, Li C. Disassembly of Death-associated Protein Kinase and DANGER Interaction Mediates Hippocampal CA1 Neuron Death in Rat Cerebral Ischemic Reperfusion. Neuroscience. 2021;471:11-19.

3 Yin XH, Han YL, Zhuang Y, Yan JZ, Li C. Geldanamycin inhibits Fas signaling pathway and protects neurons against ischemia. Neurosci Res. 2017;124:33-39.

4 Liu DH, Yuan FG, Hu SQ, Diao F, Wu YP, Zong YY, Song T, Li C, Zhang GY. Endogenous nitric oxide induces activation of apoptosis signal-regulating kinase 1 via S-nitrosylation in rat hippocampus during cerebral ischemia-reperfusion. Neuroscience. 2013; 229:36-48.

5 Wei XW, Yan H, Xu B, Wu YP, Li C, Zhang GY. Neuroprotection of co-activation of GABA receptors by preventing caspase-3 denitrosylation in KA-inducedseizures. Brain Res Bull. 2012;88(6):617-23.

6 Li C, Feng JJ, Wu YP, Zhang GY. Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation. Biochemistry (Mosc). 2012;77(6):671-8.

7 Zhang HJ, Li C, Zhang GY. ATPA induced GluR5-containing kainite receptor S-nitrosylation via activation of GluR5-Gq-PLC-IP(3)R pathway and signalling module GluR5•PSD-95•nNOS. Int J Biochem Cell Biol. 2012;44(12):2261-71.

8 Li C, Xu B, Wang WW, Yu XJ, Zhu J, Yu HM, Han D, Pei DS, Zhang GY. Coactivation of GABA receptors inhibits the JNK3 apoptotic pathway via disassembly of GluR6-PSD-95-MLK3 signaling module in KA-induced seizure. Epilepsia. 2010;51(3):391-403.