Biography

Dr. Wen-Qi Meng is a Professor in the Faculty of Naval Medicine, Naval Medical University. He received his PhD in Biochemical Engineering from the Nanjing Tech University in 2021. His research focuses on rapid detection and toxicity mechanism studies of toxic compounds. He has been awarded multiple talent honors including Young Science and Technology Talent of PLA, Shanghai Oriental Talent Program, and Shanghai Rising-Star Program. He has presided over 12 research projects and published more than 30 SCI-indexed papers as the first or corresponding author, with the highest impact factor reaching 60.6. He also serves as a committee member of the Disaster and Emergency Toxicology Committee under the Chinese Society of Toxicology, and a member of the Environmental Stress and Health Damage committee under the Chinese Environmental Mutagen Society.

Education

Nanjing Tech University, 09/2018 – 06/2021, PhD

Xuzhou Medical University, 09/2012 – 06/2015, Master of Science

Xuzhou Medical University, 09/2008 – 06/2012, Bachelor of Science

Publications:

1. Wen-Qi Meng*, Adam C Sedgwick, Nahyun Kwon, Mingxue Sun, Kai Xiao*, Xiao-Peng He*, Eric V Anslyn*, Tony D James*, Juyoung Yoon*,Fluorescent probes for the detection of chemical warfare agents. Chem. Soc. Rev., 2023, 52, 601-662. (IF 60.6, ESI Highly Cited Paper)

2. Junhong Liu, Yin Gong, Linwen Tan, Jinfeng Cen, Mo Li, Chuyu Wang, Xuan Zhao, Mingxue Sun*, Qitao Tan*, Wen-Qi Meng*, Three in one fluorescent sensing and imaging of chemical warfare agents. Nat. Comm., Nat Commun. 2026, 17(1):6583. (IF 18.1)

3. Yin Gong, Shanshan Zhang, Anying Wei, Xiang Ji, Xiaodan Chong, Jinfeng Cen, Xuan Zhao, Zimeng Luo, Zhipeng Pei, Guanchao Mao, Xinkang Zhang, Mingxue Sun, Zhiguo Sun*, Zifei Yin*, Zhengrong Zou*, Wen-Qi Meng*, Affinity-based Protein Profiling Revealed that HIGD1A is a Direct Target Protein of Aristolochic Acids. Adv. Sci., 2025: e13117.

4. Yuping Zhu, Xiaodan Chong, Zimeng Luo, Xuan Zhao, Junhong Liu, Jiasheng Chen, Wei Liu*, Ling Zhang*, Wen-Qi Meng*. Visual detection and discrimination of nerve and blood agents using a dual-site fluorescent probe in living cells and mice. J Hazard Mater. 2024, 472: 134604.

5. Wenqi Meng, Zhipeng Pei, Yurun Wang, Mingxue Sun, Qingqiang Xu, Jinfeng Cen, Kai Guo, Kai Xiao* and Zhenjiang Li*. Two birds with one stone: the detection of nerve agents and AChE activity with an ICT-ESIPT-based fluorescence sensor. J Hazard Mater. 2021, 410(15): 124811.

6. Shanshan Zhang, Yin Gong, Jinfeng Cen, Zhipeng Pei, Anying Wei, Zimeng Luo, Xuan Zhao, Guanchao Mao, Xinkang Zhang, Qingqiang Xu, Mingxue Sun, Wen-Qi Meng*. Dichloroacetate protects against sulfur mustard-induced neurotoxicity via the PDK/PDH axis and Akt/Nrf2 pathway. Free Radic Biol Med. 2025, 229: 154-167.

7. Xiaodan Chong, Zimeng Luo, Junhong Liu, Wenli Jiang, Jinfeng Cen, Yin Gong, Linwen Tan, Zhipeng Pei, Gengxi Jiang*, Yuping Zhu*, Wen-Qi Meng*. Enzyme-Activated Dual-Locked Probes for Detecting Nitroreductase and Carboxylesterase, Chem & Biomed Imaging, 2025, doi.org/10.1021/cbmi.5c00124

8. Jiayi Ying, Zimeng Luo, Qiaoan Zhang, Huyan Chen, Wei Wang, Qianqian Wang, Min Jiang, Lei-Hong Xiang*, Jing Luan*, Wen-Qi Meng*, A dual-locked fluorescent probe for imaging of human primary melanocytes and melanoma tissues via tyrosinase and hydrogen sulfide activation, Spectrochim Acta A Mol Biomol Spectrosc., 2026, 350: 127418.

9. Zimeng Luo, Mo Li, Xin Ling, Junhong Liu, Jinfeng Cen, Mingxue Sun, Wenjun Chang, Xiangdong Xu, Ling Zhang and Wen-Qi Meng*. Dual-responsive fluorescent sensors for the detection and discrimination of sulphur and nitrogen mustard. Analyst, 2025,150(19):4313-4319. (IF 3.4, Analyst HOT Articles 2025)

10. Mingxue Sun*, Zhipeng Pei, Jiahui Chen, Shanshan Zhang, Jinfeng Cen, Fangyuan Gao*, Wen-Qi Meng*. Dual-channel discrimination of two lethal chemical warfare agents using an ESIPT-ICT-based fluorescent probe. Spectrochim Acta A Mol Biomol Spectrosc. 2025, 325:125179.

HONORS AND AWARDS

• Young Elite      Scientist Sponsorship Program, China Association for Science and      Technology (CAST)

• Shanghai Rising-Star      Program, Shanghai Science and Technology Committee

• Shanghai Oriental      Talent, Shanghai Municipal Talent Work Bureau

• Outstanding Report      Award, 11th National Congress of Toxicology, China (2024)

• Excellent Paper      Award, Joint Academic Conference of Neurotoxicology and Epigenetic      Toxicology, Chinese Society of Toxicology (2023)

RESEARCH GRANTS (Principal Investigator - Recent)

INVITED CONFERENCE PRESENTATIONS

• Meng, W.      Application of Activity-Based Probes in Studying the Toxicology of      Chemical Warfare Agents. 2025 Annual Conference of the Disaster and      Emergency Toxicology Committee, Chinese Society of Toxicology,      Shihezi, China. May 2025.

• Meng, W.      Application of Fluorescent Probes in Chemical Defense Medicine Research. 2025      Symposium on Special Medicine Strategy, Xi'an, China. Sep 2025.

• Meng, W.      Toxicological Mechanisms of Mustard Agent-Induced Skin Injury Revealed by      Activity-Based Probe Technology. 11th National Congress of Toxicology,      Chinese Society of Toxicology, Suzhou, China. Sep 2024.

• Meng, W.      Application of Chemical Probe Technology in Chemical Defense Medicine      Research. 2023 Military Naval Medicine Development Forum, Shanghai,      China. Dec 2023.

• Meng, W.      Mechanisms of Sulfur Mustard-Induced Neurotoxicity. Joint Academic      Conference of Neurotoxicology and Epigenetic Toxicology, Chinese Society      of Toxicology, Guilin, China. July 2023.

• Meng, W.      Application of ABPP and Fluorescent Probe Technologies in Chemical Warfare      Agent Research. 33rd Annual Academic Conference of the Chinese Chemical      Society, Qingdao, China. June 2023.

• Meng, W.      Application of Fluorescent Probes in Chemical Defense Medicine. 15th      Conference on Bioinorganic Chemistry of the Chinese Chemical Society,      Taiyuan, China. Oct 2021.

• Meng, W.      Application of Fluorescent Probe Technology in Studying Sulfur      Mustard-Induced Nerve Injury. 2020 Academic Annual Meeting of the      Neurotoxicology Committee, Chinese Society of Toxicology, Xi'an, China.      Dec 2020.

• Meng, W.      Development and Toxicological Application of Sulfur Mustard Fluorescent      Probes. 9th Shanghai Marine Drug Young Scientist Symposium,      Shanghai, China. Oct 2020.

• Meng, W.      Development and Application of a Sulfur Mustard Fluorescent Probe Based on      a Thioketone Recognition Group. 9th National Congress of Toxicology,      Chinese Society of Toxicology, Taiyuan, China. Sep 2019.

PROFESSIONAL SERVICE AND MEMBERSHIPS

Memberships:

• Committee Member,      Disaster and Emergency Toxicology Committee, Chinese Society of Toxicology

• Committee Member,      Environmental Stress and Health Damage Committee, Chinese Environmental      Mutagen Society

• Young Committee      Member, Neurotoxicology Committee, Chinese Society of Toxicology

• Young Committee      Member, the Toxicological Analysis Branch, China Association for      Instrumental Analysis