Biography

Dr. Jianteng Zhou received his PhD from the University of Science and Technology of China in 2023 and joined the School of Life Sciences, Xuzhou Medical University, in the same year as a Lecturer. He has published five SCI-indexed papers as first author and contributed to more than 20 SCI-indexed publications, including work in Briefings in Bioinformatics, JCI Insight, iScience, and Clinical Genetics.

His research focuses on male reproductive genetics and multi-omics analysis. Using family-based whole-exome sequencing (WES) and other omics approaches, he has identified dozens of pathogenic variants associated with human infertility. He currently leads projects supported by the National Natural Science Foundation of China, the Jiangsu Innovation and Entrepreneurship Doctoral Talent Program, and Xuzhou Medical University.

Education

University of Science and Technology of China, 2023, PhD

Publications:

1. Zhou, J. ^#, Mustafa, G. ^#, Lin, T. ^#, Ye, J., Zhang, H., Jiang, H., Yang, K., Huang, G., and Shi, Q. (2026). Loss-of-Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture. Andrology. 10.1111/andr.70272.

2. Zhou, J. ^#, Li, Y. ^#, Zhu, T., Yang, K., Zhang, C., Zhang, R., Zhang, X., Zhou, D., Ding, X., Qiao, Y., et al. (2025). Single-cell analysis of testicular bacterial microbiome changes during aging and effect on reproductive capacity in mice. iScience 28, 114174. 10.1016/j.isci.2025.114174.

3. Zhou, J. ^#, Zhang, B. ^#, Zeb, A., Ma, A., Chen, J., Zhao, D., Rahim, F., Khan, R., Zhang, H., Zhang, Y., et al. (2023). A recessive ACTL7A founder variant leads to male infertility due to acrosome detachment in Pakistani Pashtuns. Clinical Genetics 104, 564-570. 10.1111/cge.14383.

4. Zhou, J. ^#, Gao, J. ^#, Zhang, H. ^#, Zhao, D., Li, A., Iqbal, F., Shi, Q., and Zhang, Y. (2020). PedMiner: a tool for linkage analysis-based identification of disease-associated variants using family based whole-exome sequencing data. Brief Bioinform. 10.1093/bib/bbaa077.

5. Ma, A. ^#, Zhou, J. ^#, Ali, H. ^#, Abbas, T., Ali, I., Muhammad, Z., Dil, S., Chen, J., Huang, X., Ma, H., et al. (2023). Loss-of-function mutations in CFAP57 cause multiple morphological abnormalities of the flagella in humans and mice. JCI insight 8. 10.1172/jci.insight.166869.