As a key laboratory of Xuzhou City, the "Physiological Function and Injury Laboratory" boasts significant advantages in both scientific research infrastructure and resource reserves.
In terms of instrumentation, the laboratory is equipped with a range of advanced devices designed for functional testing. Notable equipment includes a small animal electrocardiograph, capable of accurately recording the electrical activity of small animal hearts; an ion imaging system that visualizes dynamic changes in cellular ion concentrations; a PowerLab pressure/volume signal collector, which efficiently gathers relevant physiological data for the analysis of multiple physiological functions; in vitro heart function testing equipment that allows researchers to study the physiological characteristics of the heart after it is removed from the body; a single-cell systolic collection system for studying systolic function at the single-cell level; and a patch-clamp system, a powerful tool for examining ion channels at both cellular and molecular levels.
In terms of experimental space, the laboratory features a fully equipped cell culture room, with strictly controlled environmental conditions to ensure optimal cell growth and culture. The animal operating room meets high standards, providing a safe and standardized environment for various animal experiments. Additionally, the molecular biology laboratory is outfitted with a comprehensive set of equipment to meet diverse experimental needs in molecular research.
The laboratory also boasts an extensive reserve of scientific research resources. It maintains a rich collection of cell and animal models, including human embryonic stem cell-derived cardiomyocytes (hESC-CM) and human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM), which provide valuable cell samples for myocardial research. Additionally, multiple gene knockout mouse models are available, enabling researchers to investigate physiological functions and disease mechanisms at the genetic level. These high-quality resources provide a solid foundation for training master's students, doctoral students, and postdoctoral researchers, significantly advancing scientific research and talent development in related fields.
