On the afternoon of January 11th, the School of Basic Medical Sciences successfully hosted an Academic Salon and a National Natural Science Foundation Lecture in Room B302 of the Science and Education Building on the main campus. The event featured an invited lecture by Professor Xu Guangyin from Soochow University, Vice Chairman of the Chinese Society of Neuroscience, who delivered an insightful presentation on cutting-edge developments in the field. The event attracted faculty members and students from the School of Basic Medical Sciences, the School of Clinical Medicine, and the School of Anesthesiology, fostering a dynamic exchange of knowledge and ideas. The session was chaired by Professor Yang Dejun from the Jiangsu Provincial Key Laboratory of Brain Disease Bioinformatics, who facilitated in-depth discussions and academic engagement among attendees. This academic gathering provided a valuable platform for interdisciplinary learning and collaboration, reinforcing the university’s commitment to advancing scientific research and academic excellence.
In the first stage of the activity, Professor Xu Guangyin introduced the characteristics of chronic pain and the importance of pain research under the topic of "Purine receptors and chronic pain". He summarized the main content of pain research and shared his major scientific research achievements on purine receptor P2X2/3Rs in the past thirty years from six aspects, including peripheral inflammation sensitized P2X2/3Rs receptors; CaMKII mediates the transport of P2X2/3Rs receptors; P2X2/3Rs receptors are involved in chronic visceral pain; P2X2/3Rs DNA demethylation promotes pain in diabetes; The endogenous ligand miRNA-1306-3p of P2X2/3Rs receptor directly activates P2X2/3Rs in primary sensory neurons, inducing visceral pain and the loop mechanism of PVN as a pain "sorting center". The achievements highlighted in the report have been published in internationally renowned academic journals such as PNAS, Gut, Diabetes, and Pain. Professor Xu emphasized the importance of adhering to the "four orientations" of technological innovation and contributing to the development of a strong technological nation. He underscored the necessity for researchers to conduct rigorous and impactful studies that address critical scientific and technological challenges within China.
Following the presentation, Professor Xu engaged in an in-depth discussion with attending faculty members and students, addressing various scientific questions and fostering a dynamic exchange of ideas.
In the second phase of the event, aimed at enhancing the quality of National Natural Science Foundation (NSFC) grant proposals, Professor Xu provided detailed guidance on the preparation of bidding documents. He offered comprehensive insights into critical aspects such as innovative topic selection, the synthesis and refinement of experimental techniques, research content, and key innovations within the proposals. Attendees found the session highly beneficial, expressing their commitment to refining their applications based on the expert recommendations provided.
This event served as a valuable platform for academic exchange, fostering interdisciplinary collaboration and scientific innovation. It also contributed to the advancement of high-quality research and development in related fields.



